Research Advancements

New Study Links High-Dose Flu Vaccine to Lower Alzheimer’s Disease Risk

Posted on by Manda Hufstedler

A recent study suggests that getting your yearly flu shot, especially at a higher dose, may help protect your brain health as you age. Researchers studied data from nearly 200,000 adults aged 65 and older and found that those who received a high-dose flu vaccine were less likely to develop Alzheimer’s disease compared to those who received the standard dose. While the regular flu shot lowered Alzheimer’s risk by about 40%, the high-dose version was linked to an even greater reduction (nearly 55%). 

These findings show the strong connection between overall immune health and brain health. As we get older, our immune system naturally weakens, and high-dose vaccines are designed to provide additional protection. Experts say that staying up to date on vaccines may do more than prevent illness; it could also be a simple way to support long-term brain health. 

To read more, visit this link. 

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Turn Up the Volume on Brain Health: How Hearing Aids May Ease Dementia Symptoms

Posted on by Manda Hufstedler

We’ve highlighted in the past how important hearing is in keeping your brain healthy. Research shows that hearing loss is quite common among older adults, affecting up to 80%–90% of the population. It can also lead to social isolation, stress, and a lower quality of life. Recent studies have strengthened this connection, especially for people living with dementia. In a large study looking at data from over 10,000 participants from the National Alzheimer's Coordinating Center, researchers found that those with dementia who used hearing aids tended to experience fewer symptoms like depression, anxiety, and agitation. Though, hearing loss on its own wasn’t always linked to more severe behavioral and mood symptoms. This study highlights that addressing hearing loss can be a practical, easy way to improve the well-being of people with dementia.  

To learn more, visit this link.

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New Gene Found to be Risk Factor for Early Frontotemporal Dementia

Posted on by Manda Hufstedler

Thanks to a large international group of research participants, scientists have discovered a gene called GOLGA8A. This gene may be linked to a rare subtype of frontotemporal dementia (FTD), an early-onset dementia affecting behavior and language. The study shows that differences in this gene could influence how specific parts of the brain develop and work, which might help explain why some people are more likely to develop FTD than others. This finding adds to the growing understanding that genetics play an important role in diseases that affect the brain and nervous system and could lead to earlier detection and more personalized treatment in the future.  

To learn more, visit this link. To access the original scientific article, visit this link. 

New Gene Found to Be a Risk Factor for Early Frontotemporal Dementia

Could a Nasal Swab Help Catch Alzheimer’s Disease Sooner?

Posted on by Manda Hufstedler

Researchers at Duke Health are exploring a simple nasal swab test that may help detect early signs of Alzheimer’s disease before symptoms appear. By analyzing early biological changes in the body, this non-invasive approach could make screening more accessible and improve early diagnosis. While still in development, this promising tool highlights how easier, more accessible approaches may change how we detect and study Alzheimer’s disease in the future. 

To learn more, visit this link.

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Spring 2026 Newsletter

Posted on by Manda Hufstedler

Learn how to support your brain in the spring edition of the NC Brain Health newsletter. This issue highlights helpful brain health tips, research opportunities, and upcoming community events happening across North Carolina.

Thank you for being part of our community. Your support helps advance brain health research and education throughout the state.

Click here to view the full newsletter and join us on Facebook.

Study Highlight – Music Therapy for Caregivers of People with Parkinson’s Disease

Posted on by Manda Hufstedler

Many of you emailed us asking how to get involved in research. All our supported studies can be found on our website under the Registry Studies tab. We plan to share a research study each month. This month, we are highlighting the latest study: Music Therapy for Caregivers of People with Parkinson’s Disease (MY CARE TO TAKE CARE RESEARCH STUDY), a four-week online study on music therapy and mindful movement for care partners of people with Parkinson’s disease. If you are interested in participating, please fill out the Studies Interest Form at this link.

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A Vaccine for Your Brain: Surprising Benefits of the Shingles Shot

Posted on by Manda Hufstedler

A new study offers encouraging news about both brain and immune health. The shingles vaccine, which is already recommended for adults age 50+ to prevent a painful viral infection, may also help lower dementia risk and even slow its progression. Researchers analyzing health data from more than 280,000 older adults in Wales and Australia found that people who received the shingles vaccine were less likely to develop mild cognitive impairment or dementia. Researchers found that, among those already living with dementia, vaccinated individuals had a significantly lower risk of dying over nine years. Scientists believe the vaccine may reduce harmful inflammation in the nervous system or strengthen the immune system, though more research is needed to understand why these benefits occur. While not a guaranteed preventive measure, experts agree that discussing the shingles vaccine with your doctor is a simple, accessible step that may support healthier aging and brain health.

To read more, visit this link.

Jan Eblast_Benefits of the Shingles Shot

The Connection Between Oral Health and the Brain

Posted on by Manda Hufstedler

A new study suggests that adults with gum disease may be more likely to show signs of damage in their brain's white matter, changes linked to memory problems, slower thinking, balance issues, and higher stroke risk. Researchers found that those with gum disease had more white matter hyperintensities on brain scans, even after accounting for age, blood pressure, diabetes, and smoking. While the study does not prove that gum disease causes brain changes, it strengthens growing evidence that oral health and brain health may be connected. Experts note that gum disease can be prevented and treated, and maintaining good dental hygiene is an important step in supporting long-term brain health. 

To learn more, visit this link.

Jan Eblast_Connection between oral health and the brain

The Hidden Toll: Depression Among Dementia Caregivers

Posted on by Manda Hufstedler

Caregivers of people with dementia are at greater risk for depression. The National Health and Aging Trends Study (NHATS) and the National Study of Caregiving (NSOC), two research studies involving 526 people, recently identified some factors that may help lower caregivers' risk of depression. They found participating in caregiver training and having a partner, spouse, and friends to talk to lowered the risk of depression.

Experts highlight the importance of acknowledging the challenges that caregivers face and ensuring they have access to mental health support, respite care, and community resources.

To learn more about this research, visit this link.

The Duke Dementia Family Support Program provides tailored support for those caring for someone with dementia. This program is available to folks with or without a connection to Duke Health. To learn more, visit their website.

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Caregivers Know Best: Dementia Programs Beat “Usual Care”

Posted on by Manda Hufstedler

Dementia caregivers are asking for personalized help, and it works. New findings confirm that caregivers feel most supported when they receive resources and guidance tailored specifically to their situation and the unique challenges of dementia. Providing this focused support benefits both the caregiver's well-being and the person they care for.

To read the full article, visit this link. You can also read the full scientific article at this link.

Nov Eblast_Caregivers know best